I absolutely loved this movie. I know it was a mixed bag on reviews, and many people I talked to say it was a let down with laughs ("the trailer was funnier"), but wow it packed a punch. Apatow does a very good job of bringing the humor and craziness out of very real issues in life.

http://www.youtube.com/watch?v=hhq_T2RyLpg I don't know if anyone has mentioned this yet. This sex scene is hysterical and very illuminating. I remember Tea Leoni promoting this on one of the late night shows saying that this is the opposite of the "I'll have what she's having" diner scene from When Harry Met Sally. And the fact that she is depressed right after apparently great sex highlights one of the big dichotomies that fuel this movie - the enjoyment versus the demonization of pleasure - or as Christina says at some point, "food, sex - all that is good in life.)