Chris Westfield at 2012-04-29 22:54:18:
Audience - if it's a universal story that can reach/touch a lot of people, write a screenplay. If the story is so niche that only a specific audience/community would enjoy it, maybe a novel is better.
Appeal - Do you see this on the big screen and do you think it would do well? There's great stories and then there's great movies. Sometimes they're not the same thing.
Length - If you can't see the story fit in under two hours, then maybe you're better off writing a novel. If it's episodic, maybe TV.
That's all I can think of right now.